Left ventricular systolic function assessment in patients with dilated heart failure using cardiovascular magnetic resonance

Cardiovascular magnetic resonance (CMR) has become a reference standard for the measurement of cardiac volumes, function, and mass. This study aims to reconstruct three dimensional modeling of the left ventricle (LV) in patients with heart failure (HF) using CMRtools and thereby derive the LV functional indices. CMR images were acquired in 41 subjects (6 females) with heart failure (HF) and 12 normal controls (4 females). Five comparisons were made (i) normal and dilated heart failure subjects, (ii) male and female normal heart, (iii) male and female dilated heart, (iv) male normal and dilated heart failure and (v) female normal and dilated heart failure. In HF, a significant higher values of EDV (320 ± 79 vs. 126 ± 22 ml, P<0.0001), ESV (255 ± 68 vs. 54 ± 12 ml, P<0.00001) and lower values of EF (20 ± 7 vs. 58 ± 5 %) were found compared that of normal control. There were significant difference on LV EDV and ESV between sex in both normal and HF subjects.